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HHMI - Howard Hughes Medical Institute

At the Howard Hughes Medical Institute, we believe in the power of individuals to advance science through research and science education, making discoveries that benefit humanity. Learn more about how we move science forward. Sangeeta Bhatia Investigator »
Research Aug 04 2022
Fishnet Shell Formed by Jumbo Phages Offers Protection Against Bacterial Host Defenses

The large viruses known as jumbo phages employ a curious counter-defense strategy to protect their DNA while attacking bacteria. Now, scientists have identified the key protein involved and solved its structure.

Science Education Jul 28 2022
HHMI Awards 51 New Gilliam Fellowships to Advance Diversity and Inclusion in Science

Fifty-one graduate students and their advisers are joining the thriving community supported by the HHMI Gilliam Fellowships for Advanced Study.

Research Jul 08 2022
DNA Typewriter Taps Out a Record Inside Cells

To test their DNA typewriter, scientists sought to hide well-known phrases inside cells. But this invention’s most powerful application may lie in documenting the biological events that unfold within the boundaries of normal and diseased cells.

Research Jul 01 2022
A Souped-Up Gene Promoter Stops Heat from Sapping Plant Defenses

Plants’ immune defenses falter during heat waves, rendering them more vulnerable to insects and pathogens under climate change. HHMI scientists have now figured out why high temperatures knock out a key defense system and they’ve come up with a strategy that bolsters plant immunity.

Research Jun 10 2022
Scientists Have Found Neurons that Control Some Symptoms of Sickness

Feeling ill is about both the body and the brain. Now scientists have identified a group of neurons in mice that has ultimate control over symptoms such as fever and behaviors like seeking out warmth.

Research Jun 09 2022
Anti-Aging Clues Lurk in Lysosomes, the Recycling Centers of the Cell

Scientists have discovered that lysosomes in roundworms produce molecules that allow cells to ‘talk’ to one another about aging, coordinating the process across the entire organism.

INSTITUTE May 26 2022
New Program Pledges $1.5 Billion for Early Career Faculty Committed to Diversity, Equity, and Inclusion

The Freeman Hrabowski Scholars Program will support up to 150 early career scientists for their research and their efforts to create labs in which everyone can thrive. Applications to the program are open now.

Research May 18 2022
Spying on Thousands of Neurons in the Brain’s Vision Center Simultaneously

Neurons across eight areas of the brain team up to process visual information. Researchers have now documented these neurons’ activity at a breadth and resolution never before reported.

Research May 11 2022
Structure of ‘Gliding Bird’ Plant Protein Could Lead to Better Crops

When pathogens attack, the NPR1 protein steps in to control a plant’s immune response. Scientists have now figured out what the protein looks like and how it works – a possible boon for agriculture.

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Research Aug 04 2022
Fishnet Shell Formed by Jumbo Phages Offers Protection Against Bacterial Host Defenses

The large viruses known as jumbo phages employ a curious counter-defense strategy to protect their DNA while attacking bacteria. Now, scientists have identified the key protein involved and solved its structure.

Science Education Jul 28 2022
HHMI Awards 51 New Gilliam Fellowships to Advance Diversity and Inclusion in Science

Fifty-one graduate students and their advisers are joining the thriving community supported by the HHMI Gilliam Fellowships for Advanced Study.

Research Jul 08 2022
DNA Typewriter Taps Out a Record Inside Cells

To test their DNA typewriter, scientists sought to hide well-known phrases inside cells. But this invention’s most powerful application may lie in documenting the biological events that unfold within the boundaries of normal and diseased cells.

Research Jul 01 2022
A Souped-Up Gene Promoter Stops Heat from Sapping Plant Defenses

Plants’ immune defenses falter during heat waves, rendering them more vulnerable to insects and pathogens under climate change. HHMI scientists have now figured out why high temperatures knock out a key defense system and they’ve come up with a strategy that bolsters plant immunity.

Research Jun 10 2022
Scientists Have Found Neurons that Control Some Symptoms of Sickness

Feeling ill is about both the body and the brain. Now scientists have identified a group of neurons in mice that has ultimate control over symptoms such as fever and behaviors like seeking out warmth.

Research Jun 09 2022
Anti-Aging Clues Lurk in Lysosomes, the Recycling Centers of the Cell

Scientists have discovered that lysosomes in roundworms produce molecules that allow cells to ‘talk’ to one another about aging, coordinating the process across the entire organism.

INSTITUTE May 26 2022
New Program Pledges $1.5 Billion for Early Career Faculty Committed to Diversity, Equity, and Inclusion

The Freeman Hrabowski Scholars Program will support up to 150 early career scientists for their research and their efforts to create labs in which everyone can thrive. Applications to the program are open now.

Research May 18 2022
Spying on Thousands of Neurons in the Brain’s Vision Center Simultaneously

Neurons across eight areas of the brain team up to process visual information. Researchers have now documented these neurons’ activity at a breadth and resolution never before reported.

Research May 11 2022
Structure of ‘Gliding Bird’ Plant Protein Could Lead to Better Crops

When pathogens attack, the NPR1 protein steps in to control a plant’s immune response. Scientists have now figured out what the protein looks like and how it works – a possible boon for agriculture.

Science Forward
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